Additionally, at least one card should clear away Sludge on a grand scale
Natural remedy (Nature)(Rarity+Cost to be determined)
Use: Discards all Sludge cards in play
Also, there should be at least one card that attacks Toxic cards directly, probably by forcing their discard and damaging the opponent for having them similar to Cleansing.
Attack cards with the Toxic keyword could include such themes as plagued rats, poisonous jellies, and seeping swampland (Nature+Toxic?).
As an additional idea, if Sludge were one of the cards that Danai present granted, would that make it a better card?